Cholestatic Pruritus

Cholestatic pruritus is a common, often unrelenting and debilitating condition characterized by very itchy skin in patients with cholestatic liver diseases such as primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC). This form of pruritus is often not relieved by scratching and not responsive to currently available medications, which are largely non-specific and associated with significant side effects.

ALBUNIQUE MAY ADDRESS THE CAUSE OF THE PRURITIS

Clinical Trial

Albunique Study (AS-XXX-XXX): Albutec Inc is conducting the Albunique Study to determine the safety of extracorporeal albumin dialysis (ECAD) system containing albumin in the dialysis fluid recycled using the Hepalbin Charcoal Adsorbent to improve pruritus in patients with chronic liver disease. ECAD therapy will consist of two 6-hour treatments over 3 days. Pruritus score and Itch severity scale will be determined by the patient weekly and by a physician at baseline and 1 month, 2 month and 6-month follow-up exams.

Patient Resources

The following resources can provide more information about cholestatic pruritus:

American Liver Foundation

Canadian PBC Society

Global Liver Institute

PBCers.org

PBC Foundation

PSC Partners Seeking a Cure

PSC Support